Case Report: Primary Leptomeningeal Melanoma in a Patient with Neurocutaneous Melanosis
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منابع مشابه
Giant Congenital Melanocytic Nevi and Neurocutaneous Melanosis
Introduction. The major medical concern with giant congenital melanocytic nevi CMN is high risk of developing cutaneous melanoma, leptomeningeal melanoma, and neurocutaneous melanocytosis. Case Report. A 30-year-old woman with a giant congenital melanocytic nevus covering nearly the entire right thoracodorsal region and multiple disseminated melanocytic nevi presented with neurological symptoms...
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Neurocutaneous melanosis (NCM) is a rare congenital syndrome characterized by the presence of large or multiple congenital melanocytic nevi with either benign or malignant pigmented cell tumors of the leptomeninges. We report a case of NCM in a patient with previously robust health. No neurological deficit was noted in the patient. At the age of 21 years old, blurred vision initially appeared. ...
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Background: This case report presents a very rare Dandy-Walker malformation (DWM) in association with a sporadic condition characterized by congenital melanocytic nevi and melanocytic thickening of the leptomeninges called Neurocutaneous melanosis (NCM). The DWM is a rare congenital disorder characterized by enlarged posterior fossa and a cystic enlargement of the four...
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Neurocutaneous melanosis is a rare neurocutaneous syndrome defi ned by the presence of multiple and /or giant congenital cutaneous nevi and melanocytic deposits in the central nervous system with the infi ltration of leptomeninges. The major medical concern with giant congenital cutaneous nevi is high risk of developing cutaneous melanoma, leptomeningeal melanoma, and neurocutaneous melanosis. ...
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The concept of neurocutaneous melanosis was described in 1948 by Van Bogaert [1] as a nonfamilial neuroectodermal dysplasia, but the first report of an individual with stigmata of neurocutaneous melanosis was made by Rokitansky [2] in 1861. The criteria to be met for diagnosis are large multiple pigmented skin nevi (more than 20 em in diameter) with an excess of melanotic cells in the leptomeni...
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